Fractalkine receptor is expressed in mature ovarian teratomas and required for epidermal lineage differentiation

Rooper, Lisa; Gurler, Hilal; Kajdacsy-Balla, Andre A; Barbolina, Maria V

doi:10.1186/1757-2215-6-57

Journal of Ovarian Research

Table 2 Expression of CX3CR1 in human fetal tissues

From: Fractalkine receptor is expressed in mature ovarian teratomas and required for epidermal lineage differentiation

Position	Number	Sex*	Age*	Organ*	Type*	Intensity**	Location	Percentage***	Score****	Notes
A1	1	M	5 mon.	Heart	Normal	2.5		100	250
A2	2	M	5 mon.	Heart	Normal	2.5		100	250
A3	3	M	5 mon.	Heart	Normal	2.5		100	250
A4	4	M	5 mon.	Gallbladder	Normal	2		100	200
A5	5	M	5 mon.	Gallbladder	Normal	2		60	120
A6	6	M	5 mon.	Gallbladder	Normal	2		90	180
A7	7	M	5 mon.	Colon	Normal	3		100	300
A8	8	M	5 mon.	Colon	Normal	3		100	300
A9	9	M	5 mon.	Colon	Normal	3		100	300
B1	10	M	5 mon.	Small intestine	Normal	2.5		100	250
B2	11	M	5 mon.	Small intestine	Normal	2.5		100	250
B3	12	M	5 mon.	Small intestine	Normal	2.5		100	250
B4	13	M	5 mon.	Liver	Normal	2.5		100	250
B5	14	M	5 mon.	Liver	Normal	3		100	300
B6	15	M	5 mon.	Liver	Normal	3		100	300
B7	16	M	5 mon.	Rectum	Normal	2.5		95	237.5
B8	17	M	5 mon.	Rectum	Normal	2		95	190
B9	18	M	5 mon.	Rectum	Normal	2.5		100	250
C1	19	M	5 mon.	Stomach	Normal	2		70	140
C2	20	M	5 mon.	Stomach	Normal	1.5		60	90
C3	21	M	5 mon.	Stomach	Normal	1.5		80	120
C4	22	M	5 mon.	Adrenal gland	Normal	2.5		80	200
C5	23	M	5 mon.	Adrenal gland	Normal	2		90	180
C6	24	M	5 mon.	Adrenal gland	Normal	2		60	120
C7	25	M	5 mon.	Thyroid gland	Normal	0.5		30	15
C8	26	M	5 mon.	Thyroid gland	Normal	0.5		10	5
C9	27	M	5 mon.	Thyroid gland	Normal	0.5		10	5
D1	28	M	5 mon.	Spleen	Normal	1		80	80
D2	29	M	5 mon.	Spleen	Normal	1		80	80
D3	30	M	5 mon.	Spleen	Normal	1		80	80
D4	31	M	5 mon.	Thymus gland	Normal	2.5	Epithelioid cells	20	50
D4						1	Lymphocytes	100	100
D5	32	M	5 mon.	Thymus gland	Normal	2.5	Epithelioid cells	20	50
D5						1	Lymphocytes	100	100
D6	33	M	5 mon.	Thymus gland	Normal	2.5	Epithelioid cells	20	50
D6						1	Lymphocytes	100	100
D7	34	M	5 mon.	Skin	Normal	2	Epithelium	80	160
D7						3	Adipose	70	210
D8	35	M	5 mon.	Skin	Normal	1.5	Epithelium	80	120
D8						3	Adipose	70	210
D9	36	M	5 mon.	Skin	Normal	2	Epithelium	90	180
D9						3	Adipose	80	240
E1	37	M	5 mon.	Bone	Normal	2.5		30	75
E2	38	M	5 mon.	Bone	Normal	2.5		30	75
E3	39	M	5 mon.	Bone	Normal	2.5		30	75
E4	40	M	5 mon.	Epididymis	Normal	1		90	90
E5	41	M	5 mon.	Epididymis	Normal	0.5		60	30
E6	42	M	5 mon.	Epididymis	Normal	0.5		70	35
E7	43	M	5 mon.	Brain	Normal	2		20	40
E8	44	M	5 mon.	Brain	Normal	1		5	5
E9	45	M	5 mon.	Brain	Normal	1		5	5
F1	46	M	5 mon.	Lung and trachea	Normal	3	Trachea	90	270
F1	46	M	5 mon.	Lung and trachea	Normal	3	Alveoli	25	75
F2	47	M	5 mon.	Lung and trachea	Normal	3	Trachea	90	270
F2	47	M	5 mon.	Lung and trachea	Normal	1	Alveoli	25	25
F3	48	M	5 mon.	Lung and trachea	Normal	3	Trachea	80	240
F3	48	M	5 mon.	Lung and trachea	Normal	1	Alveoli	25	25
F4	49	M	5 mon.	Muscle	Normal	0.5		100	50
F5	50	M	5 mon.	Muscle	Normal	0.5		100	50
F6	51	M	5 mon.	Muscle	Normal	0.5		100	50
F7	52	M	5 mon.	Smooth muscle	Normal	2		100	200
F8	53	M	5 mon.	Smooth muscle	Normal	2		100	200
F9	54	M	5 mon.	Smooth muscle	Normal	2		100	200
G1	55	M	5 mon.	Kidney	Normal	2	Tubules	80	160
G1	55	M	5 mon.	Kidney	Normal	1	Glomeruli	50	50
G2	56	M	5 mon.	Kidney	Normal	2.5	Tubules	70	175
G2	56	M	5 mon.	Kidney	Normal	0.5	Glomeruli	30	15
G3	57	M	5 mon.	Kidney	Normal	1.5	Tubules	90	135
G3	57	M	5 mon.	Kidney	Normal	0.5	Glomeruli	70	35
G4	58	M	5 mon.	Eye	Normal	3		100	300	Retinal pigment epithelium
G5	59	M	5 mon.	Eye	Normal	3		100	300	Retinal pigment epithelium
G6	60	M	5 mon.	Eye	Normal	3		100	300	Retinal pigment epithelium
G7	61	F	5 mon.	Umbilical cord	Normal	2		100	200
G8	62	F	5 mon.	Umbilical cord	Normal	1.5		100	150
G9	63	F	5 mon.	Umbilical cord	Normal	NA		NA	NA
H1	64	F	5 mon.	Placenta	Normal	0.5		20	10
H2	65	F	5 mon.	Placenta	Normal	0.5		10	5
H3	66	F	5 mon.	Placenta	Normal	0.5		40	20
H4	67	F	5 mon.	Uterus	Normal	0.5		20	10
H5	68	F	5 mon.	Uterus	Normal	0.5		5	2.5
H6	69	F	5 mon.	Uterus	Normal	0.5		20	10
H7	70	F	5 mon.	Pancreas	Normal	2	Acini and ducts	80	160
H8	71	F	5 mon.	Pancreas	Normal	2.5	Acini and ducts	80	200
H9	72	F	5 mon.	Pancreas	Normal	2.5	Acini and ducts	70	175
I1	73	F	5 mon.	Ovary	Normal	3		70	210
I2	74	F	5 mon.	Ovary	Normal	3		80	240
I3	75	F	5 mon.	Ovary	Normal	3		90	270
I4	76	F	5 mon.	Fallopian tube	Normal	0.5		5	2.5
I5	77	F	5 mon.	Fallopian tube	Normal	1		10	10
I6	78	F	5 mon.	Fallopian tube	Normal	1.5		5	7.5

* Information obtained from the manufacturer (US Biomax; Rockville, MD) for the multiple organ fetal tissue array BE01014; TMA contained triplicate cores (26cases/78cores).
** Intensity of staining was scored as negative (0), weak positive (1), moderate positive (2), and strong positive (3).
*** Denotes percentage of positive cells in the core.
**** Score has been calculated as intensity multiplied by percentage of positive cells.

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ISSN: 1757-2215

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