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Figure 4 | Journal of Ovarian Research

Figure 4

From: PRIMA-1 increases cisplatin sensitivity in chemoresistant ovarian cancer cells with p53 mutation: a requirement for Akt down-regulation

Figure 4

PRIMA-1 increases p-p53 content in chemoresistant p53-mutant ovarian cancer cells treated with CDDP when Akt was down-regulated. Changes in p-p53 (Ser15) content following PRIMA-1 and/or CDDP treatment with/without Akt down-regulation were assessed by Western blot. Results are normalized against GAPDH and expressed as fold of control. * p<0.05 vs CDDP & DN-Akt; Values are mean ± SEM of three independent experiments

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Journal of Ovarian Research

ISSN: 1757-2215

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