Table 3 8-OHdG alteration associated with overall survival of serous ovarian cancer patients (N = 72)
From: The significance of the alteration of 8-OHdG in serous ovarian carcinoma
Characteristic | Univariate analysis | p value | Multivariate analysis | p value | ||
|---|---|---|---|---|---|---|
| Â | HR | 95Â % CI | Â | HR | 95Â % CI | Â |
FIGO stage | Â | Â | Â | |||
  I | 1.00 | Reference |  | 1.00 | Reference |  |
  II | 1.42 | 0.68-6.25 |  | 1.21 | 0.43-8.02 |  |
  III | 6.78 | 1.66-18.41 |  | 2.25 | 1.24-6.08 |  |
  IV | 9.43 | 3.61-27.87 | <0.01 | 3.28 | 1.47-9.54 | <0.01 |
Grade | 4.12 | 1.35-12.69 | <0.01 | 2.57 | 1.62-3.45 | <0.01 |
Suboptimal CRS | 2.16 | 1.25-3.85 | <0.01 | 1.65 | 1.19-2.55 | 0.02 |
Ascites | 1.47 | 1.26-3.04 | 0.01 | 1.23 | 1.08-2.36 | 0.04 |
Nadir CA-125 level | 1.02 | 1.01-1.04 | <0.01 | 1.01 | 1.00-1.03 | <0.01 |
p53 positive | 1.30 | 1.09-4.39 | 0.02 | 1.13 | 0.96-2.41 | 0.10 |
8-OHdG (T/A) | 1.35 | 1.13-3.42 | <0.01 | 1.18 | 1.01-2.07 | <0.01 |
hOGG1 protein (T/A) | 0.84 | 0.78-1.06 | 0.54 | 0.89 | 0. 88–1.02 | 0.65 |
Age | 1.01 | 1.00-1.01 | 0.04 | 1.00 | 0.98-1.01 | 0.21 |