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Figure 1 | Journal of Ovarian Research

Figure 1

From: Analysis of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human ovarian tumors and the effects of chemical LSD1 inhibitors in ovarian cancer cell lines

Figure 1

Analysis of LSD1 mRNA by qRT-PCR in our study cohort reveals robus LSD1 mRNA levels in all ovarian normal and tumor specimens tested. qRT-PCR analysis of LSD1 mRNA levels in n = 177 ovarian specimens. ‘N’ indicates bulk ovarian normal tissue. ‘I-IV’ indicates FIGO stage. Two LSD1 mRNA replicates were measured per specimen (shown in grey and black) and their values were normalized to the levels of ACTB mRNA measured in the same specimen also in duplicate by qRT-PCR. The y-axis refers to the relative levels of LSD1 mRNA with respect to ACTB mRNA (as a percentage). The x-axis includes tumor identification numbers. FIGO grade: borderline (cantaloupe), grade G1 (light blue), grade G2 (blue), and grade G3 (dark blue); as well as tumor histological subtype: endometrioid (green), clear cell (yellow), mucinous (purple), serous (red), and papillary serous (cayenne) are indicated on top of each tumor identification number (when available). In a few cases (as indicated), specimens are classified in more than one histological subtype.

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Journal of Ovarian Research

ISSN: 1757-2215

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