Table 1 Some of the common proteins in exosomes
From: Exosomes: an overview of biogenesis, composition and role in ovarian cancer
Antigen presentation | MVB formation | Signal transduction | Heat shock | Tetraspanin | Adhesion molecules |
|---|---|---|---|---|---|
MHC I | Alix | Gi2a, Gi3a, Gsa, FRL, Erk2, Fyn | Hsp70 | CD9 | CD146, CD166 |
MHC II | TSG101 | Hsp84 | CD37 | ICAM-1, ALCAM | |
CD86 | Gag | Sh2 phosphatase | Hsp90 | CD53 | MAC-1, Integrins a3, a4, aM, b1, b2 |
RhoA, C, GDI | CD63 | ||||
Syntenin, CBL | CD81 | LFA3, CD53, | |||
Catenin, LCK | CD82 | CD326 | |||
CD11a, b, c | |||||
Membrane | Cytoskeletal | Miscellaneous | Lipid Raft | Enzymes | |
Transport & Fusion | Proteins | Associated | |||
AP-1, Arp2/3, SNAP | Radixin | Thioredoxine | P-Selectin | LBPA | ATP Citrate lyase |
Syntaxin | Advillin | peroxidase | CD18, CD147 | Cholesterol | ATPase |
Clathrin | |||||
Dynamin | Vimentin | Histone 1, 2, 3 | Complement factor 3 | Flotillin-1 | G6P Isomerase |
Rab5,7, Rap1B | Talin, CAP1 | MVP, CD26, CD13 | CD55 | Stomatin | Peroxiredoxin 1 |
RabGDI | Ezrin, Actin | CD59 | |||
Asp amino- transferase | |||||
a-enolase | |||||
Annexins (I, II, IV, V, VI) | Tubulin | Ferritin light chain 1, 2 | Aldehyde reductase | ||
Moesin | FA Synthase | ||||
Cofilin | Pyruvate kinase | ||||
References: | 15, 6, 72,73 |