Table 2 Sensitivity and specificity for different cut-off values
Biomarker | Cut-off value | Sensitivity (%) | Specificity (%) |
|---|---|---|---|
Premenopausal | |||
HE4 | 93 pM | 50 | 92.9 |
CA125 | 18.5 U/ml | 100 | 41.4 |
CA125 | 180 U/ml | 40 | 96 |
ROMA | 3.45% | 100 | 22.2 |
ROMA | 28.5% | 40 | 92.9 |
Postmenopausal | |||
HE4 | 66 pM | 90 | 62.7 |
HE4 | 79 pM | 50 | 80.4 |
CA125 | 35 U/ml | 60 | 90.2 |
CA125 | 60 U/ml | 70 | 76.5 |
ROMA | 16.2% | 90 | 47.1 |
ROMA | 34.9% | 70 | 86.3 |
ROMABOT | 8% | 90 | 43.1 |
ROMABOT | 16% | 70 | 76.5 |