“Platelet-associated regulatory system (PARS)” with particular reference to female reproduction

Table 1 Platelet surface and soluble molecules

Surface molecules	Soluble molecules	Molecules with effect to platelets
GP Ib-IX	Plasminogen activator inhibitor-1	Fibrinogen
GP IIb-IIIa	α2-antiplasmin	vWF
ICAM-2	Fibrinogen	CD40 ligand
P-selectin	Factor V	Monoclonal antibody F11
F11 receptor	β-thromboglobulins	Leukocyte β2 integrin LFA-1
TLRs	Chemokine RANTES	Leukocyte β2 integrin Mac-1
Chemokine receptors	IL-1α	DC-SIGN
JAM-A	IL-1β	PSGL-1
JAM-C	IL-1RA	hCG
CD63	PF4	Progesterone
Benzodiazepine-receptor	PAF	Estradiol
	EGF
	PDGF
	Insulin-like growth factor 1
	TGFβ
	Thrombospondin
	Fibronectin
	vWF
	ADP
	ATP
	Histamine
	Serotonin

GP Ib-IX, Glycoprotein Ib-IX; GP IIb-IIIa, Glycoprotein IIb-IIIa; ICAM-2, Intercellular adhesion molecule 2; TLRs, Toll-like receptors; PF4, Platelet factor 4; PAF, Platelet-activating factor; EGF, Epidermal growth factor; PDGF, Platelet-derived growth factor; TGFβ, Transforming growth factor beta; vWF, von Willebrand Factor; ADP, Adenosine diphosphate; ATP, Adenosine triphosphate; DC-SIGN, Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin; PSGL-1, P-selectin glycoprotein ligand-1.

ISSN: 1757-2215