Figure 4
Immunohistochemical staining for SOX7, cyclinD1 and COX2 in normal ovarian tissues, borderline ovarian tumors and ovarian cancer. A. SOX7 strong positive staining in normal ovarian tissues and weak positive staining in borderline ovarian tumor and ovarian cancer. CyclinD1 weak positive staining in normal ovarian tissues and borderline ovarian tumor, strong positive staining in ovarian cancer. COX2 weak positive staining in normal ovarian tissues, strong positive staining in borderline ovarian tumor and ovarian cancer. B. SOX7 localizes to the nucleus in in every SOX7-positive ovarian tissue section. Representative of section (20 × magnification) immunohistochemical stains of normal ovarian tissues, borderline ovarian tumors and ovarian cancer with anti-SOX7 antibody shown, from left to right, negative (a), weak (b), moderate (c) and strong stain (d).