Table 2 IVF outcomes
From: Oocyte zona pellucida dysmorphology is associated with diminished in-vitro fertilization success
Dysmorphic oocytes | Normal oocytes | Dysmorphic vs. Normal oocytes | Dysmorphic vs. Normal oocytes 4 | |
|---|---|---|---|---|
N = 119 | N = 77 | Difference 1 /RR 2 / IRR 3 [95% CI] | Difference 1 /RR 2 / IRR 3 [95% CI] | |
P-value | P-value | |||
Transferred embryo per cycle | 3.1 (1.2) | 2.7 (1.2) | 0.4 [0.06, 0.8] | 0.25 [−0.07, 0.57] |
Mean (SD) | P = 0.021 | P = 0.128 | ||
Embryos fertilized per cycle | 6.35 (3.68) | 8.47 (3.98) | −2.1 [−3.2, −1.0] | −1.91 [−3.00, −0.81] |
Mean (SD) | P < 0.001 | P < 0.001 | ||
Blastulation rate per cycle | .26 | .42 | IRR = 0.61 [0.51, 0.73] | IRR = 0.68 [0.56, 0.82] |
blasts/embryos fertilized | 202/756 | 274/652 | P < 0.001 | P < 0.001 |
Fertilization rate per cycle | .85 | .85 | IRR = 0.99 [0.90, 1.11] | IRR = 1.00 [0.90, 1.11] |
fertilized /oocytes inseminated | 832/ 891 | 652/766 | P = 0.953 | P = 0.935 |
Implantation rate | .17 | .36 | IRR = 0.48 [0.34, 0.68] | IRR = 0.52 [0.37, 0.73] |
sacs/embryos transferred | 61/354 | 72/202 | P < 0.001 | P < 0.001 |
Clinical Pregnancy rate per cycle | 44% | 70% | RR = 0.62 [0.48, 0.80] | RR = 0.64 [0.49, 0.82] |
52/119 | 54/77 | P < 0.001 | P < 0.001 | |
Live Birth rate per cycle | 29% | 52% | RR = 0.55 [0.39, 0.79] | RR = 0.60 [0.42, 0.87] |
34/119 | 40/77 | P = 0.001 | P = 0.007 | |
Miscarriage rate | 35% | 26% | RR = 1.34 [0.74, 2.40] | RR = 1.28 [0.73, 2.25] |
18/52 | 14/54 | P = 0.333 | P = 0.396 |