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Table 1 Included articles characteristics that examined the FSHR N680S polymorphism association with ovarian response

From: Evaluating influence of the genotypes in the follicle-stimulating hormone receptor (FSHR) Ser680Asn (rs6166) polymorphism on poor and hyper-responders to ovarian stimulation: a meta-analysis

First author PY [R] Country Ethnic group Sample size Type of ovarian response Used HWE Addressed LD Tissue source Genotyping CBS
Daelemans 2004 [36] Belgium NHC 229 Hyper/controls No Yes blood DNA sequencing 4
Klinkert 2006 [38] Nether-lands NHC 105 Poor, not poor No Yes blood Taqman 5
Livshyts 2009 [39] Ukraine NHC 374 poor, good/controls Yes Yes blood PCR-RFLP 5
Boudjenah 2012 [1] France NHC 427 poor, hyper/controls Yes Yes blood Multiplex PCR 7
Binder 2012 [42] Germany NHC 259 low, control No No blood RT-QPCR 6
Mohiyiddeen 2013 [40] United Kingdom NHC 504 poor, normal, hyper Yes Yes blood Taqman 5
de Castro 2003 [37] Spain HC 102 poor, good Yes Yes blood RT-QPCR 5
de Castro 2004 [13] Spain HC 170 poor, rest of patients, high Yes No blood RT-QPCR 8
Huang 2014 [4] China Asian 1,250 Poor, good responders Yes Yes blood MALDI-TOF 8
Achrekar 2009 [35] India Asian 150 Hyper, not hyper Yes No blood RT-QPCR 5
Yan 2013 [41] China Asian 450 Poor, not poor, hyper, not hyper Yes Yes blood RT-QPCR 6
  1. PY: Publication Year; [R]: Reference; NHC: Non-Hispanic Caucasian; HC: Hispanic Caucasian; HWE: Hardy-Weinberg Equilibrium; LD: Linkage Disequilibrium PCR: Polymerase Chain Reaction; RFLP: Restriction Fragment Length Polymorphism; RT-QPCR: Real-Time Quality Polymerase Chain Reaction; MALDI-TOF: Matrix Assisted Laser Desorption Ionization-Time-of-Flight; CBS: Clark-Baudouin Score: assessment of methodological quality of the included studies.
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Journal of Ovarian Research

ISSN: 1757-2215

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