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Figure 2 | Journal of Ovarian Research

Figure 2

From: Evidence for induction of a tumor metastasis-receptive microenvironment for ovarian cancer cells in bone marrow and other organs as an unwanted and underestimated side effect of chemotherapy/radiotherapy

Figure 2

Chemotherapy and irradiation create a pro-metastatic microenvironment in various murine organs that chemoattract A2780 cells. qRT-PCR detection of A2780 human ovarian cancer cells in bone marrow (BM), liver, lung, and spleen after irradiation (1000 cGy) and chemotherapy (cisplatin). Five mice were employed per group. The results from two independent experiments are combined and shown as mean ± SD. *p < 0.05 or **p < 0.005 compared with control (organs neither irradiated nor received cisplatin).

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