Table 2 Molecular markers differentially expressed by OSCs and oocytes. Only few markers are maintained in the differentiating process. The cell membrane isoforms of Ddx-4 and SSEA-4 are detectable on OSCs [12, 15, 17, 23–26]
Ovarian stem cells | Oocytes |
|---|---|
Ddx-4 (cell membrane and cytoplasm) | Ddx-4 (cytoplasm) |
SSEA-4 (cell membrane and cytoplasm) | SSEA-4 (cytoplasm) |
OCT-4 A and B | OCT-4 B |
c-kit | c-kit |
DAZL (nucleus and cytoplasm) | DAZL (cytoplasm) |
Fragilis | ZP (zona pellucida proteins) |
CD133 | GDF-9 (growth differentiation factor 9) |
Stella | NOBOX (newborn ovary hemeobox protein) |
Nanog | SCP-3 (synaptonemal complex protein 3) |
Sox-2 | |
Blimp-1 |