Fig. 4
From: NPR2 is involved in FSH-mediated mouse oocyte meiotic resumption
The effects of U0126 on FSH- and EGF-induced oocyte meiotic resumption and NPR2 mRNA expression in COCs at 4 h. a The GVBD rates after stimulation with FSH, EGF, FSH plus U0126 or EGF plus U0126 in COCs. b The mRNA expression of NPR2 after stimulation with FSH, EGF, FSH plus U0126 or EGF plus U0126 in COCs. c The phosphorylation of MAPK3/1 after stimulation with FSH, EGF, FSH plus U0126 or EGF plus U0126 in COCs. The results are presented as the mean ± SEM and are representative of three independent experiments. C: Control; E: EGF; U: U0126; F: FSH. Different letters represent significant differences (P < 0.05)