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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Small putative NANOG, SOX2, and SSEA-4-positive stem cells resembling very small embryonic-like stem cells in sections of ovarian tissue in patients with ovarian cancer

Fig. 5

Ovarian tissue sections with “chambers” of different shapes containing groups of small, round cells (arrows). These small cells had diameters of up to 5 μm. Their nuclei filled almost the whole cell volumes in two patients with high-grade serous ovarian carcinoma after HE staining (a-f). A proportion of these cells were NANOG-positive (g and h). “Chambers” were surrounded by epithelial/cancer cells. Figures a, b, c, e and f show the same structures at different magnifications to get better insight. (Light microscope: a-g, magnifications 100x, 200x and 1000x; inverted microscope: h, magnification 200x). Legend: brown-NANOG-positivity, blue-nuclei after HE staining. Red Bars: 10 μm for h and 100 μm for a-g

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Journal of Ovarian Research

ISSN: 1757-2215

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