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Table 3 Genes with a 2-fold up- or down-regulation between 0 and 12 h

From: Changes in gene expression of histone modification enzymes in rat granulosa cells undergoing luteinization during ovulation

Genes Modifications Fold P value
Upregulated    
NEK6 (NIMA (never in mitosis gene a)-related kinase 6) Histone Phosphorylation 2.02 0.0002
CIITA (Class II, major histocompatibility complex, transactivator) Histone Acetyltransferases 2.29 0.0085
Downregulated    
AURKC (Aurora kinase C) Histone Phosphorylation −3.51 0.0008
AURKB (Aurora kinase B) Histone Phosphorylation −2.83 0.0017
HDAC10 (Histone deacetylase 10) Histone Deacetylases −2.65 0.0026
SETDB2 (SET domain, bifurcated 2) Histone Methyltransferases −3.11 0.0030
HDAC4 (Histone deacetylase 4) Histone Deacetylases −2.14 0.0029
EZH2 (Enhancer of zeste homolog 2 (Drosophila)) Histone Methyltransferases: −2.55 0.0050
PAK1 (P21 protein (Cdc42/Rac)-activated kinase 1) Histone Phosphorylation −4.21 0.0044
CDK2 (Cyclin dependent kinase 2) Histone Phosphorylation −2.00 0.0099