Table 3 Genes with a 2-fold up- or down-regulation between 0 and 12 h

Upregulated

  NEK6 (NIMA (never in mitosis gene a)-related kinase 6)

Histone Phosphorylation

2.02

0.0002

  CIITA (Class II, major histocompatibility complex, transactivator)

Histone Acetyltransferases

2.29

0.0085

Downregulated

  AURKC (Aurora kinase C)

Histone Phosphorylation

−3.51

0.0008

  AURKB (Aurora kinase B)

Histone Phosphorylation

−2.83

0.0017

  HDAC10 (Histone deacetylase 10)

Histone Deacetylases

−2.65

0.0026

  SETDB2 (SET domain, bifurcated 2)

Histone Methyltransferases

−3.11

0.0030

  HDAC4 (Histone deacetylase 4)

Histone Deacetylases

−2.14

0.0029

  EZH2 (Enhancer of zeste homolog 2 (Drosophila))

Histone Methyltransferases:

−2.55

0.0050

  PAK1 (P21 protein (Cdc42/Rac)-activated kinase 1)

Histone Phosphorylation

−4.21

0.0044

  CDK2 (Cyclin dependent kinase 2)

Histone Phosphorylation

−2.00

0.0099