Table 2 Ovarian cell lines used in biomarker screening

OV-2008

Dr.Stephen B.Howell, UCSD

Endometrioid carcinoma

-

-

Tumor

N/A

2774

Dr.Judith Wolf, MD Anderson Cancer Center, Texas

Endometrioid carcinoma

2

Ascitic fluid

N/A

A2780

Dr.Stephen B. Howell, UCSD

Ovarian carcinoma

-

-

Tumor

N/A

BG-1

Dr.Korach, NIH

Adenocarcinoma

-

II

Tumor

N/A

CAOV-3

ATCC

Adenocarcinoma

-

-

Tumor

FAM123B, STK11, TP53

CSOC 882

Dr. Karlan, UCLA

Adenocarcinoma

3

IC

Tumor

EGFR, HER2,

DOV13

Dr.Robert Bast JR., MD Anderson Cancer Center

Adenocarcinoma

-

-

Ascites

N/A

ES-2

ATCC

Clear cell carcinoma

3

-

Tumor

P glycoprotein

HEY

Dr.Stephen B.Howell, UCSD

Adenocarcinoma

-

-

Xenografted ovarian tumor

KRAS + BRAF

IGROV-1

Dr.Stephen B.Howell, UCSD

Adenocarcinoma

2

III

Tumor

N/A

OV-90

ATCC

Malignant papillary serous adenocarcinoma

3

IIIC

Ascites

her2/neu +, p53

PA-1

ATCC

Teratocarcinoma

-

-

Ascites

N-ras + (activated)

SKOV-1

Dr.Stephen B.Howell, UCSD

Clear cell carcinoma

-

-

Ovary

N/A

SK-OV-3

ATCC

Adenocarcinoma

-

-

Ascites

MLH1, CDKN2A, TP53,PIK3CA

SW-626

ATCC

Adenocarcinoma

-

-

Ovary

N/A

TOV-112D

ATCC

Malignant adenocarcinoma

3

IIIC

Tumor

her2/neu +, p53

TOV-21G

ATCC

Malignant adenocarcinoma

3

III

Tumor

p53+ (WT)

UCI 101

Dr.Philip Carpenter, UCI

Papillary Seous Adenocarcinoma

-

III

Ascites and Tumor

p-glycoprotein, EGFR

UCI 107

Dr.Philip Carpenter, UCI

Papillary Adenocarcinoma

-

III

Tumor

N/A

FHIOSE 118

Dr.Cheng, Moffit Cancer Center,

Immortal normal ovarian surface epithelium

-

-

-

N/A

IOSE 523

Dr.Nelly Auersperg, University of British Columbia, Canada

Normal ovarian epithelium

-

-

-

N/A