Table 4 Factors associated with post-surgical adverse DOR at 6 months after laparoscopic cystectomy
Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
Adverse DOR (n = 38) | Non-adverse DOR (n = 74) | P value | OR (95 % CI) | P value | |
Patient characteristics | |||||
Age (years) | 34.6 ± 5.0 (33.0–36.3) | 33.0 ± 4.8 (31.8–34.1) | 0.09 | ||
Gravidity | 0.2 ± 0.6 (0.03–0.5) | 0.1 ± 0.4 (0.03–0.2) | 0.30 | ||
Parity | 0.2 ± 0.6 (0.1–0.6) | 0.1 ± 0.3 (0–0.2) | 0.15 | ||
Body mass index (kg/m2) | 21.7 ± 4.5 (20.2–23.2) | 21.3 ± 5.2 (20.1–22.6) | 0.73 | ||
Laterality of cysts | |||||
Unilateral | 15 (39.5) | 49 (66.2) | 0.007 | 3.71 (1.45–9.51) | 0.006 |
Bilateral | 23 (60.5) | 25 (33.8) | |||
Total size of ovarian cyst (mm) | 75.4 ± 32.9 (64.6–86.2) | 71.9 ± 24.4 (66.2–77.5) | 0.52 | ||
Pre-surgical serum hormone concentrations | |||||
LH (mIU/mL) | 4.7 ± 4.0 (3.4–6.0) | 6.9 ± 10.0 (4.6–9.2) | 0.18 | ||
FSH (mIU/mL) | 6.7 ± 2.4 (5.9–7.5) | 6.4 ± 3.9 (5.4–7.3) | 0.67 | ||
Estradiol (pg/mL) | 74.1 ± 89.3 (44.8–103.4) | 71.4 ± 86.7 (51.3–91.5) | 0.88 | ||
CA125 (U/mL) | 71.3 ± 48.5 (55.4–87.3) | 67.6 ± 55.4 (54.8–80.4) | 0.72 | ||
AMH (ng/mL) | 2.5 ± 1.2 (2.1–2.9) | 4.8 ± 3.1 (4.0–5.5) | <0.001 | 0.43 (0.27–0.67) | <0.001 |
Peri-surgical findings | |||||
Re-ASRM score | 61.8 ± 33.7 (50.8–72.9) | 48.9 ± 26.3 (42.8–55.0) | 0.03 | − | − |
Total surgical duration (min) | 89.8 ± 40.8 (76.4–103.2) | 82.8 ± 32.3 (75.3–90.2) | 0.32 | ||
Total blood loss (mL) | 37.4 ± 45.5 (22.5–52.4) | 25.4 ± 28.0 (18.9–31.8) | 0.09 | ||