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Table 2 Variants outside of hotspot locations of 50 cancer genes

From: Establishment and characterization of a cell line (HCH-1) originating from a human clear cell carcinoma of the ovary

  Chromosome Position Ref Allele Variant Allele Type Frequency Variant Type Allele Sourcea Gene Symbol Coverage AA Ref AA Variant
1 chr3 178917005 A G Heterozygous 40.2 SNP Novel PIK3CA 1950 unknown unknown
2 chr4 1807894 G A Homozygous 100 SNP Novel FGFR3 1222 T T
3 chr4 55141055 A G Homozygous 100 SNP Novel PDGFRA 1755 I I
4 chr4 55972974 T A Homozygous 100 SNP Novel KDR 1987 Q H
5 chr4 153249443 C T Homozygous 100 SNP Novel FBXW7 1998 V V
6 chr5 112175770 G A Homozygous 100 SNP Novel APC 1981 A A
7 chr5 149433596 TG GA Heterozygous 32.1 MNP Novel CSF1R 1993 unknown unknown
8 chr7 55249063 G A Heterozygous 52.1 SNP Novel EGFR 1999 Q Q
9 chr13 28610183 A G Homozygous 100 SNP Novel FLT3 1999 unknown unknown
10 chr17 7579472 G C Heterozygous 49.2 SNP Novel TP53 1976 P R
11 chr19 1220321 T C Heterozygous 55.4 SNP Novel STK11 1894 unknown unknown
12 chr20 57484611 G A Heterozygous 48.9 SNP Novel GNAS 1994 R H
  1. Ref reference, AA amino Acid
  2. aAllele Source, whether a variant is hotspot: Novel or Hotspot