Table 2 Correlation of topoisomerase isoenzymes with clinical stage of all EOC patients

TOP1

I

19

55

4.47 (0.57 − 34.8)

0.12

II

43

16

2.54 (0.81 − 7.91)

0.096

III

718

264

1.18 (0.97 − 1.42)

0.096

IV

69

97

1.17 (0.8 − 1.71)

0.43

TOP2A

I

37

37

10.37 (3.04−35.44)

5.8e − 06

II

25

34

2.04 (0.68 − 6.11)

0.19

III

277

705

1.21 (1−1.46)

0.053

IV

74

92

0.76 (0.52 − 1.13)

0.18

TOP2B

I

34

40

4.64 (1.02 − 21.21)

0.029

II

24

35

0.29 (0.09 − 0.94)

0.028

III

249

719

0.87 (0.72 − 1.06)

0.18

IV

94

72

1.4 (0.96 − 2.06)

0.082

TOP3A

I

54

20

1.84 (0.58 − 5.8)

0.29

II

42

17

0.44 (0.1 − 1.98)

0.27

III

716

266

0.7 (0.57 − 0.86)

0.00045

IV

59

107

0.74 (0.5 − 1.09)

0.13

TOP3B

I

42

32

3.05 (0.91 − 10.2)

0.057

II

35

24

1.76 (0.58 − 5.33)

0.31

III

675

307

0.75 (0.63 − 0.91)

0.003

IV

64

102

0.73 (0.5 − 1.08)

0.11