Fig. 3
a Mean (± SEM) intrafollicular concentrations (ng/ml) of testosterone (T), androstenedione (A4), estrone, estradiol (E2), and progesterone (P4) at the time of ovariectomy and coincidentally with the 8th FSH dose in control (C; yellow), prenatal testosterone-treated (T; red), prenatal T plus postnatal flutamide (T + F; blue), and prenatal T plus postnatal rosiglitazone (T + R; gray) females. See Fig. 1 for synchronization and controlled ovarian stimulation protocol and text for prenatal/postnatal treatment details. Within group comparisons: asterisks represent differences within group within hormone and between follicular sizes. Posthoc analyses performed only when overall ANOVA among all three sizes was significant. Comparisons between C and T group are represented by a ≠ b if P < 0.05 and by a’ ≠ b’if P = 0.07. F: flutamide; R: rosiglitazone. Data obtained from one 3 mm, one 4 mm, and two 5-6 mm follicles randomly selected from each female. b Percent change in intrafollicular steroids of T, A4, estrone, E2, and P4 between 3 and 5-6 mm follicles in C (yellow), T (red), T + F (blue), T + R (black) groups. Percent change was calculated by subtracting the overall mean values between the 3 and 5-6 mm size within each group