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Table 1 Clinicopathological characteristics of the patients

From: Preoperative HE4, CA125 and ROMA in the differential diagnosis of benign and malignant adnexal masses

Pathology All patients n (%) Menopausal status
Pre- n (%) Post- n (%)
Benign ovarian diseases 128 87 41
 Histologic type
 Serous 46 (35.9) 25 (28.7) 21 (51.2)
 Mucinous 13 (10.2) 7 (8.1) 6 (14.6)
 Endometriosis 33 (25.8) 31 (35.6) 2 (4.9)
 Mixed 12 (9.4) 8 (9.2) 4 (9.8)
 Other 24 (18.7) 16 (18.4) 8 (19.5)
Epithelial ovarian cancer 96 33 63
 Histologic type
 Serous 59 (61.5) 17 (51.4) 42 (66.7)
 Endometrioid 13 (13.5) 5 (15.2) 8 (12.7)
 Mucinous 10 (10.4) 6 (18.2) 4 (6.3)
 Clear cell 5 (5.2) 3 (9.1) 2 (3.2)
 Mixed/Undifferentiated 8 (8.3) 2 (6.1) 6 (9.5)
 No data 1 (1.1) 0 (0) 1 (1.6)
FIGO stage
 IA 5 (5.2) 3 (9.1) 2 (3.2)
 IB 4 (4.1) 2 (6.1) 2 (3.2)
 IC 15 (15.6) 8 (24.3) 7 (11.1)
 IIA 2 (2.1) 0 (0) 2 (3.2)
 IIB 1 (1.1) 1 (3.0) 0 (0)
 IIC 8 (8.3) 3 (9.1) 5 (7.9)
 IIIA 3 (3.1) 1 (3.0) 2 (3.2)
 IIIB 9 (9.4) 1 (3.0) 8 (12.7)
 IIIC 36 (37.5) 11 (33.3) 25 (39.6)
 IV 12 (12.5) 2 (6.1) 10 (15.9)
 not staged 1 (1.1) 1 (3.0) 0 (0)
Grade
 G1 5 (5.2) 3 (9.1) 2 (3.2)
 G2 10 (10.4) 6 (18.2) 4 (6.3)
 G3 78 (81.3) 23 (69.7) 55 (87.3)
 unknown 3 (3.1) 1 (3.0) 2 (3.2)