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Table 1 Presentation of case reports of SLCTs containing malignant heterologous mesenchymal elements

From: Sertoli - Leydig cell tumor with retiform areas and overgrowth of rhabdomyosarcomatous elements: case report and literature review

Author

Patient’s age

Tumor size

Laterality

FIGO stage

Treatment

SLCT grade

Heterologous elements

Recurrence site

Recurrence treatment

Outcome

Prat et al. 1982 [18]

 

13–22 cm

        
 

23

 

Right ovary

IA

Right SO

/

Immature skeletal muscle + Immature cartilage + Gastrointestinal epithelium

Peritoneum, Pelvis

Chemotherapy

Alive with tumor after 2 years

 

24

 

Not specified

IA

Unilateral SO

/

Immature cartilage

Omentum, Pelvis

Surgery, Chemotherapy

Died after 18 months

 

14

 

Left ovary

IA

Left SO

Poor differentitation

Cartilage in recurrent tumor

Pelvis

Radiotherapy

Died after 9 months

 

16

 

Right ovary

IA

Right SO

/

Immature skeletal muscle

Left ovary, Peritoneum

TAH + Left SO; Chemotherapy

Died after 7 years

 

20

 

Not specified

IIA

TAH + Bilateral SO

Poor differentiation

Skeletal muscle in recurrent tumor

Peritoneum

Surgery, Radiotherapy, Chemotherapy

Died after 10 months

 

36

 

Right ovary

IIB

Right SO

/

Immature skeletal muscle + Immature cartilage

Peritoneum

/

Died after 6 months

 

48

 

Left ovary

IA

TAH + Left SO

/

Immature skeletal muscle + Immature cartilage

Not specified

Not specified

Not specified

 

20

 

Right ovary

IIB

Right SO + Chemotherapy

/

Immature skeletal muscle

Left ovary, Douglas pouch

TAH + Left SO; Radiotherapy

Died after 18 months

 

32

 

Right ovary

IA

TAH + Right SO

/

Immature skeletal muscle

Peritoneum

/

Died after 5 months

 

22

 

Not specified

Not specified

Biopsy

/

Immature skeletal muscle

Not specified

Not specified

Not specified

 

17

 

Left ovary

IC

Left SO

/

Immature skeletal muscle

Right ovary, Pelvis

TAH + Right SO Omentectomy

Died after 12 months

 

11

 

Left ovary

IA

Left SO

/

Immature cartilage

/

/

Alive after 10 years

Kostopolou, Talerman, 2003 [24]

22

6 cm

Left ovary

IA

Left SO

Moderate differentitation

Immature skeletal muscle

/

/

Disease free after 10 months

Grove et al. 2006 [23]

29

18 × 14 × 11 cm

Right ovary

IC

Right SO + Omentectomy

Moderate differentitation

Embrional rhabdomyosarcoma + Immature cartilage

/

/

Disease free after 48 months

Guerard, Ferenczy, 1982 [25]

16

20 × 20 × 10 cm

Left ovary

IC

Left SO

Moderate differentitation

Pleomorphic rhabdomyosarcoma

Abdomen

Surgery, Chemotherapy

Recurrence after 6 and 10 months

  1. SO salpingo-oopherectomy, TAH total abdominal histerectomy