Table 3 Performance tumour markers in predicting cytoreduction (a) or platinum sensitivity (b)
Sensitivity | Specificity | PPV | NPV | DOR | |
|---|---|---|---|---|---|
(a) | |||||
CA125 ≤ 75 UI/ml | 81.3 % | 85.7 % | 86.7 % | 80 % | 22.13 |
HE4 ≤ 252 pmol/l | 93.3 % | 50 % | 70 % | 85.7 % | 12.57 |
CA125 ≤ 75 UI/ml and HE4 ≤ 252 pmol/l | 93.7 % | 92.3 % | 93.7 % | 92.3 % | 96.15 |
(b) | |||||
CA125 ≤ 35 UI/ml | 90.9 % | 57.9 % | 55.6 % | 91.7 % | 13.75 |
HE4 ≤ 115 pmol/l | 92.9 % | 68.7 % | 72.2 % | 91.7 % | 28.6 |
CA125 ≤ 35 UI/ml and HE4 ≤ 115 pmol/l | 92.9 % | 68.7 % | 72.2 % | 91.7 % | 28.6 |