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Table 7 Effect of Rutin-I (100 mg/kg) and Rutin-II (150 mg/kg) on total cholesterol, triglycerides, HDL- C, LDL-C, VLDL-C, Non-HDL-C, TC/HDL, TG/HDL and LDL/HDL concentrations in Letrozole induced PCOS rats after 36 days of experiment

From: Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats

Parameters

Control

PCOS

Metformin

Rutin-I

Rutin-II

Total Cholesterol(mg/dL)

215.60 ± 3.43

231.10 ± 4.27

211.30 ± 6.81b*

212.21 ± 1.53b*

207.10 ± 2.24b**

Triglycerides (mg/dL)

185.11 ± 4.23

213.10 ± 5.16a*

197.40 ± 5.82

199.20 ± 6.93

186.12 ± 4.62b*

HDL-C (mg/dL)

160.70 ± 4.17

144.41 ± 3.63a*

153.21 ± 1.80

146.43 ± 4.52

159.80 ± 3.14b*

LDL-C (mg/dL)

17.83 ± 3.98

42.99 ± 1.99a**

18.58 ± 7.22b**

25.81 ± 5.11

10.05 ± 2.29b***

VLDL-C (mg/dL)

37.03 ± 0.85

42.61 ± 1.03a*

39.49 ± 1.16

39.83 ± 1.39

37.20 ± 0.92b*

Non-HDL-C(mg/dL)

54.86 ± 4.48

85.61 ± 1.50a**

58.07 ± 7.32b**

65.65 ± 4.75b*

47.24 ± 2.64b***

TC/HDL

1.34 ± 0.03

1.59 ± 0.02a***

1.38 ± 0.05b**

1.45 ± 0.04

1.29 ± 0.02b***c*

TG/HDL

1.16 ± 0.04

1.48 ± 0.06a**

1.29 ± 0.03

1.37 ± 0.06

1.17 ± 0.04b**

LDL/HDL

0.11 ± 0.03

0.29 ± 0.01a**

0.12 ± 0.05b**

0.18 ± 0.04

0.06 ± 0.02b***

  1. Values are expressed as Mean ± SEM
  2. * = p < 0.05, ** = p < 0.01, *** = p < 0.001
  3. a Value vs control, b Value vs PCOS, c Value vs Metformin