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Table 7 Effect of Rutin-I (100 mg/kg) and Rutin-II (150 mg/kg) on total cholesterol, triglycerides, HDL- C, LDL-C, VLDL-C, Non-HDL-C, TC/HDL, TG/HDL and LDL/HDL concentrations in Letrozole induced PCOS rats after 36 days of experiment

From: Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats

Parameters Control PCOS Metformin Rutin-I Rutin-II
Total Cholesterol(mg/dL) 215.60 ± 3.43 231.10 ± 4.27 211.30 ± 6.81b* 212.21 ± 1.53b* 207.10 ± 2.24b**
Triglycerides (mg/dL) 185.11 ± 4.23 213.10 ± 5.16a* 197.40 ± 5.82 199.20 ± 6.93 186.12 ± 4.62b*
HDL-C (mg/dL) 160.70 ± 4.17 144.41 ± 3.63a* 153.21 ± 1.80 146.43 ± 4.52 159.80 ± 3.14b*
LDL-C (mg/dL) 17.83 ± 3.98 42.99 ± 1.99a** 18.58 ± 7.22b** 25.81 ± 5.11 10.05 ± 2.29b***
VLDL-C (mg/dL) 37.03 ± 0.85 42.61 ± 1.03a* 39.49 ± 1.16 39.83 ± 1.39 37.20 ± 0.92b*
Non-HDL-C(mg/dL) 54.86 ± 4.48 85.61 ± 1.50a** 58.07 ± 7.32b** 65.65 ± 4.75b* 47.24 ± 2.64b***
TC/HDL 1.34 ± 0.03 1.59 ± 0.02a*** 1.38 ± 0.05b** 1.45 ± 0.04 1.29 ± 0.02b***c*
TG/HDL 1.16 ± 0.04 1.48 ± 0.06a** 1.29 ± 0.03 1.37 ± 0.06 1.17 ± 0.04b**
LDL/HDL 0.11 ± 0.03 0.29 ± 0.01a** 0.12 ± 0.05b** 0.18 ± 0.04 0.06 ± 0.02b***
  1. Values are expressed as Mean ± SEM
  2. * = p < 0.05, ** = p < 0.01, *** = p < 0.001
  3. a Value vs control, b Value vs PCOS, c Value vs Metformin