Plasma levels of MMP-7 and TIMP-1 in laboratory diagnostics and differentiation of selected histological types of epithelial ovarian cancers

Table 5 The Spearman rank correlation for MMP-7, TIMP-1, HE4 and CA125 in tested groups

			MMP-7	TIMP-1	HE4	CA125
EOC	MMP-7	R	1.00	0.24	0.35	0.27
	MMP-7	p		0.014	<0.001	0.007
	TIMP-1	R	0.24	1.00	0.24	0.30
	TIMP-1	p	0.014		0.014	0.002
	HE4	R	0.35	0.24	1.00	0.39
	HE4	p	<0.001	0.014		<0.001
	CA125	R	0.27	0.30	0.39	1.00
	CA125	p	0.007	0.002	<0.001
Benign Ovarian Tumor	MMP-7	R	1.00	0.25	0.24	0.06
	MMP-7	p		0.006	0.008	0.526
	TIMP-1	R	0.25	1.00	0.27	0.001
	TIMP-1	p	0.006		0.002	0.966
	HE4	R	0.24	0.27	1.00	0.17
	HE4	p	0.008	0.002		0.070
	CA125	R	0.06	0.001	0.17	1.00
	CA125	p	0.526	0.966	0.070
Healthy Subjects	MMP-7	R	1.00	0.12	−0.12	−0.05
	MMP-7	p		0.336	0.331	0.682
	TIMP-1	R	0.12	1.00	0.13	−0.03
	TIMP-1	p	0.336		0.286	0.794
	HE4	R	−0.12	0.13	1.00	0.14
	HE4	p	0.331	0.286		0.268
	CA125	R	−0.05	−0.03	0.14	1.00
	CA125	p	0.682	0.794	0.268

ISSN: 1757-2215