Table 6 The diagnostic criteria of the ROC curve for MMP-7, TIMP-1, HE4 and CA125 in epithelial ovarian cancer patients

Stage I

AUC

0.7801^a

0.5769

0.8343^a

0.8324^a

SE

0.0693

0.0718

0.0582

0.0471

95% C.I.

0.644–0.916

0.436–0.718

0.720–0.948

0.740–0.925

pAUC = 0.5

0.0001

0.2840

<0.001

<0.001

Stage II

AUC

0.7938^a

0.6109

0.8462^a

0.8825^a

SE

0.0639

0.0772

0.0479

0.0397

95% C.I.

0.669–0.919

0.460–0.762

0.752–0.940

0.805–0.960

pAUC = 0.5

<0.001

0.1506

<0.001

<0.001

Stage III

AUC

0.8905^a

0.7740^a

0.9521^a

0.9331^a

SE

0.0485

0.0643

0.0288

0.0327

95% C.I.

0.796–0.986

0.648–0.900

0.896–1.008

0.869–0.997

pAUC = 0.5

<0.001

<0.001

<0.001

<0.001

Stage IV

AUC

0.8679^a

0.7314^a

0.8994^a

0.9458^a

SE

0.0624

0.0778

0.0511

0.0252

95% C.I.

0.746–0.990

0.579–0.884

0.799–1.000

0.896–0.995

pAUC = 0.5

<0.001

0.0029

<0.001

<0.001

Total group

AUC

0.8335^a

0.6372^a

0.8836^a

0.8988^a

SE

0.330

0.0425

0.0263

0.0235

95% C.I.

0.769–0.898

0.554–0.721

0.832–0.935

0.853–0.945

pAUC = 0.5

<0.001

0.0013

<0.001

<0.001