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Table 2 Mean ± SEM number of primordial, primary, secondary, tertiary, graffian, cystic, atretic follicle and corpus luteum (5 sections per ovary) in control, PCOS, PCOS + Metformin and PCOS +Quercetin treated adult female rats after 21 days of treatment

From: Therapeutic potentials of Quercetin in management of polycystic ovarian syndrome using Letrozole induced rat model: a histological and a biochemical study

Developing follicles (μm)

CONTROL

PCOS

PCOS + METFORMIN

PCOS + QUERCETIN

 

Primodial

7.80 ± 0.80

7.33 ± 0.38

8.14 ± 0.47

7.85 ± 0.42

 

Primary

6.80 ± 0.33

5.50 ± 0.20

6.85 ± 0.40 b*

6.90 ± 0.31 b*

 

Secondary

2.00 ± 0.89

0.60 ± 0.15 a*

2.14 ± 0.24 b**

2.00 ± 0.53 b*

 

Tertiary

1.61 ± 0.22

0.16 ± 0.15 a***

1.30 ± 0.17 b**

1.28 ± 0.17 b**

 

Graffian

1.00 ± 0.63

0.16 ± 0.15

0.71 ± 0.17

0.85 ± 0.13

 

Cystic Follicle

0 ± 0

11.33 ± 0.45 a***

1.57 ± 0.18 a**b***

1.60 ± 0.20 a**b***

 

Atretic Follicle

2.80 ± 0.33

8.00 ± 1.82 a***

3.28 ± 0.26 b***

3.00 ± 0.20 b***

 

Corpus Luteum

3.60 ± 0.35

1.66 ± 0.20 a***

3.57 ± 0.18 b***

3.43 ± 0.18 b***

 
  1. Values are expressed as Mean ± SEM.*, **, *** indicate significance from the control group at P < 0.001, 0.01 and 0.05 probability level
  2. aValue vs control, bValue vs PCOS