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Table 3 Results of Transwell experiments and IC50 for anti-neoplastic drugs

From: Role of BMI1 in epithelial ovarian cancer: investigated via the CRISPR/Cas9 system and RNA sequencing

Group

Cell numbers (median ± SD)

IC50 (μg/ml)

Invasion

Migration

Cisplatin

Carboplatin

Paclitaxel

Wild-type SKOV3

9.2 ± 0.4

27.8 ± 3.2

5.9

14.5

16.6

BMI1 knock-out clone

4.2 ± 1.1

11.0 ± 0.7

3.4

5.2

13.6

P value

< 0.05

< 0.05

< 0.05

< 0.05

> 0.05