Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer

Table 3 Occurrence of checkpoint inhibitory molecules and TILS in tumors

Molecules in tumor sections^a	Frequency					Total patients positive
Molecules in tumor sections^a	0	1	2	3	4	Total patients positive
T-PD-1	10	35	10	0	0	45
S-PD-1	12	39	4	0	0	43
PD-L1	37	14	3	1	0	18
CD3	2	23	18	5	7	53
CD8	17	15	18	5	0	38
FoxP3	7	12	15	19	2	48

^aTumor sections of 55 ovarian and related cancers were IHC stained for molecules as indicated. Sections were visualized by microscopy and a pathological score assigned from 0 to 4, based on the frequency of expression of each molecule, where “0” indicates the absence and “4” the highest frequency of expression

ISSN: 1757-2215