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Table 3 Prognostic factors for progression-free survival (PFS) and overall survival (OS) of ovarian clear cell carcinoma patients

From: Endometriosis does not confer improved prognosis in ovarian clear cell carcinoma: a retrospective study at a single institute

Variables

5 year-PFS %

p valuea

p valueb

HR (95%CI)

5 year-OS %

p valuea

p valueb

HR (95%CI)

Endometriosis

 

0.001

0.295

  

0.013

0.677

 

 With

87.9

   

89.4

   

 Without

53.3

   

67.7

   

Age (years)

 

0.628

   

0.550

  

 < 60

72.0

   

79.6

   

 ≥60

47.8

   

69.6

   

CA-125 (U/mL)

 

0.001

0.620

  

0.142

  

 < 200

76.6

   

80.0

   

 ≥200

38.4

   

64.4

   

Parity

 

0.342

   

0.382

  

 0

70.8

   

89.5

   

 ≥1

53.6

   

75.9

   

Laterality

 

0.034

0.093

  

0.028

0.360

 

 Unilateral

70.1

   

79.3

   

 Bilateral

46.7

   

56.2

   

Tumor diameter

 

0.084

0.662

  

0.236

  

 < 10

77.7

   

83.4

   

 ≥10

59.8

   

70.0

   

Comprehensive staging

 

0.348

   

0.070

0.441

 

 Yes

68.6

   

79.0

   

 No

58.9

   

56.2

   

Residual lesion

 

0.000

0.126

  

0.001

0.731

 

 Yes

72.8

   

82.6

   

 No

25.0

   

33.3

   

Ascites

 

0.000

0.016

  

0.001

0.052

 

 Yes

45.9

  

2.78 (1.21–6.47)

60.8

   

 No

82.0

  

87.6

   

Lymph nodes status

 

0.000

0.324

  

0.012

0.395

 

 Positive

33.3

   

58.3

   

 Negative

76.0

   

85.6

   

FIGO stage

 

0.000

0.033

1.61 (1.04–2.49)

 

0.000

0.874

 

 I

88.8

  

89.9

   

 II

55.6

  

80.2

   

 III

22.4

  

45.5

   

 IV

33.3

  

33.3

   

Chemotherapy cycles

 

0.050

0.290

  

0.421

  

 ≥6

72.5

   

78.4

   

 > 6

49.9

   

69.5

   

Chemosensitivity

 

0.000

0.000

101.60 (29.45–350.49)

 

0.000

0.000

109.55

 Sensitive

87.3

  

96.5

  

(23.46–511.51)

 Resistant

0

  

9.2

  
  1. alog-rank test; b Cox-proportional hazards model