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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Effect of resveratrol and metformin on ovarian reserve and ultrastructure in PCOS: an experimental study

Fig. 5

TEM photomicrographs of control and PCOS groups. Oocyte, granulosa and theca cells of follicles in control group (a-c), in PCOS group (d-i) and in solvent group (j-l). D shows the relation between oocyte-zona pellucida-granulosa cells; e-h show granulosa cells and I shows the theca cell layer. Note the apoptotic granulosa (e, k) and theca cells (i, l) in PCOS and solvent groups. Arrows indicate expanded perivitellin (d) and intercellular spaces (d, i); arrowheads indicate expanded sER (f) and autophagosomes (e); *: lipid droplets; dashed arrows (g, h): mitochondria with degenerated cristae. Oc: oocyte, Gc: granulosa cell, Tc: theca cell, Zp: zona pellucida. Uranyl acetate and lead citrate

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