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Table 5 Factors influencing oocyte maturation (n = 920) and the number of oocytes retrieved (n = 921) after in vitro maturation

From: Live birth rate after human chorionic gonadotropin priming in vitro maturation in women with polycystic ovary syndrome

 

Oocyte maturation

Oocytes retrieved

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

β

p-value

β

p-value

β

p-value

β

p-value

Age, years

0.001

0.99

–

–

0.11

0.19

−0.08

0.31

Body mass index, kg/m2

−0.1

0.70

–

–

0.845

< 0.001

0.85

< 0.001

Anti-Müllerian hormone, ng/mL

0.31

0.15

0.32

< 0.001

0.28

0.001

0.36

< 0.001

Antral follicle count, n

0.07

0.27

  

0.002

0.88

  

Follicle stimulating hormone, IU/mL

0.26

0.53

–

–

0.14

0.39

–

–

Progesterone, ng/mL

0.35

0.41

–

–

−0.17

0.31

–

–

Luteinizing hormone, IU/L

0.48

< 0.001

−0.11

0.01

−0.09

0.04

−0.09

0.03

Free testosterone index

0.44

0.002

−0.05

0.37

−0.03

0.62

–

–

Menstrual cycles, n (%)

 Amenorrhea

Ref

Ref

–

–

Ref

Ref

–

–

 Oligomenorrhea

−6.68

0.05

−0.82

0.53

−0.82

0.54

–

–

 Regular

−5.74

0.36

–

–

−3.96

0.11

−3.97

0.08

Polycystic ovaries on ultrasound, n (%)

 Both ovaries

Ref

Ref

–

–

Ref

Ref

–

–

 One ovary

0.92

0.65

–

–

−1.06

0.26

–

–

Duration of infertility, years

0.21

0.48

–

–

−0.02

0.86

–

–

Type of infertility, n (%)

 Primary

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

 Secondary

−5.79

0.003

1.15

0.13

1.38

0.07

1.17

0.11

Number of IVF attempts, n (%)

 1

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

 2

−7.65

0.005

1.33

0.21

1.63

0.13

1.74

0.11

 3

−5.77

0.21

4.71

0.008

4.51

0.01

4.84

0.006

Indications for IVM, n (%)

 Tubal factors

Ref

Ref

–

–

Ref

Ref

–

–

 Male factors

−0.60

0.94

–

–

−2.24

0.49

–

–

 Ovulation induction failure

−1.19

0.83

–

–

3.92

0.07

4.05

0.004

 Previous OHSS with COH

−6.72

0.38

–

–

5.12

0.09

2.22

0.38

 Others

−0.90

0.80

–

–

− 0.90

0.80

–

–

  1. COH controlled ovarian hyperstimulation, IVF in vitro fertilization, IVM in vitro maturation, OHSS ovarian hyperstimulation syndrome