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Table 1 Associations of the HIF-1α polymorphisms with clinicopathological parameters of OCCC

From: Association of the hypoxia-inducible factor-1α (HIF-1α) gene polymorphisms with prognosis in ovarian clear cell carcinoma

   C1772T G1790A C1772T and/or G1790A
Variable N (%) CC CT + TT p value GG GA + AA p value CC and GG CC + TT and/or GA + AA p value
Age
  ≥ 54 43 (48) 33 10 0.571 41 2 0.474 31 12 0.518
  < 54 46 (52) 35 11   45 1   34 12  
FIGO stage
 I and II 70 (79) 55 15 0.262 68 2 0.518 53 17 0.209
 III and IV 19 (21) 13 6   18 1   12 7  
Residual tumor
 Yes 11 (12) 9 2 0.493 10 1 0.330 8 3 0.616
 No 71 (88) 59 19   76 2   57 21  
Recurrence
 Yes 23 (26) 19 4 0.306 22 1 0.597 18 5 0.358
 No 66 (74) 49 17   64 2   47 19  
Death
 Yes 15 (17) 12 3 0.506 14 1 0.429 11 4 0.625
 No 74 (83) 56 18   72 2   54 20  
  1. CC 1772CC genotype, CT 1772CT genotype, TT 1772TT genotype, GG 1790GG genotype, GA 1790GA genotype, AA 1790AA genotype, FIGO the International Federation of Obstetrics and Gynecology