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Table 1 Associations of the HIF-1α polymorphisms with clinicopathological parameters of OCCC

From: Association of the hypoxia-inducible factor-1α (HIF-1α) gene polymorphisms with prognosis in ovarian clear cell carcinoma

  

C1772T

G1790A

C1772T and/or G1790A

Variable

N (%)

CC

CT + TT

p value

GG

GA + AA

p value

CC and GG

CC + TT and/or GA + AA

p value

Age

  ≥ 54

43 (48)

33

10

0.571

41

2

0.474

31

12

0.518

  < 54

46 (52)

35

11

 

45

1

 

34

12

 

FIGO stage

 I and II

70 (79)

55

15

0.262

68

2

0.518

53

17

0.209

 III and IV

19 (21)

13

6

 

18

1

 

12

7

 

Residual tumor

 Yes

11 (12)

9

2

0.493

10

1

0.330

8

3

0.616

 No

71 (88)

59

19

 

76

2

 

57

21

 

Recurrence

 Yes

23 (26)

19

4

0.306

22

1

0.597

18

5

0.358

 No

66 (74)

49

17

 

64

2

 

47

19

 

Death

 Yes

15 (17)

12

3

0.506

14

1

0.429

11

4

0.625

 No

74 (83)

56

18

 

72

2

 

54

20

 
  1. CC 1772CC genotype, CT 1772CT genotype, TT 1772TT genotype, GG 1790GG genotype, GA 1790GA genotype, AA 1790AA genotype, FIGO the International Federation of Obstetrics and Gynecology