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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: Aberrant DNA methylation suppresses expression of estrogen receptor 1 (ESR1) in ovarian endometrioma

Fig. 3

DNA methylation statuses of ESR1, ESR2 and PGR in EE and OE samples by BeadChip. Samples from 3 subjects are shown for each sample type. a DNA methylation statuses of AB-promoter, T-DMR1, C-promoter, and T-DMR2. The locations of each upstream Exon and CpG site are shown with the distance from the TSS of upstream Exon A. A, B and C are upstream Exon A, B and C, respectively. b and c DNA methylation statuses of the region of the transcription start site of ESR2 (b) and PGR (c). Bars indicate methylation levels from 0 to 100%. Pie charts show the average DNA methylation statuses (percentage) of EE and OE at each CpG site. The DNA methylation statuses of each CpG site were compared by unpaired t-test. p < 0.05

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