Fig. 1

Multiple functions of RLIP76. RLIP76 is a modular protein harboring an N-terminal region, a Rho-Gap region, a Ral binding region, and a C-terminal region. RLIP76 is capable of interacting with diverse functional proteins through its variety of domains and motifs. Thus, RLIP76 is a multifunctional protein involved in various cellular and physiological functions such as endocytosis, metabolite transport, stress responses, mitosis, actin remodeling, cell migration and spreading