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Table 1 Patients’ characteristics of PLT-CA125 scores in FIGO stage IV ovarian cancer

From: Combined score of pretreatment platelet count and CA125 level (PLT-CA125) stratified prognosis in patients with FIGO stage IV epithelial ovarian cancer

Variables

Total

(n = 108)

PLT-CA125 score

p-valuea

0

(n = 39, %)

1

(n = 48, %)

2

(n = 21, %)

Median age, years (range)

51 (27–75)

51 (33–75)

53 (27–72)

50 (38–69)

0.664

Age, n (%)

    

0.395

  < 55

64 (59)

19 (49)

25 (52)

14 (54)

 

55

44 (41)

20 (51)

23 (48)

7 (46)

 

Histology, n (%)

    

0.709

 HGSC

85 (79)

29 (74)

39 (81)

17 (81)

 

 Non-HGSC

23 (21)

10 (26)

9 (49)

4 (19)

 

Primary treatment, n (%)

    

NA

 PDS + chemotherapy

53 (49)

21 (54)

24 (50)

8 (38)

 

 NACT+IDS

52 (48)

17 (44)

22 (46)

13 (62)

 

 Chemotherapy alone

3 (3)

1 (3)

2 (4)

0 (0)

 

Surgery, n (%)

    

0.760

 Optimal surgery

82 (76)

30 (77)

35 (73)

17 (81)

 

Suboptimal surgery/no surgery

26 (24)

9 (23)

13 (27)

4 (19)

 

Metastatic pattern, n (%)

    

0.012

Pleural effusion with positive cytology

17 (16)

5 (13)

7 (15)

5 (24)

 

 LNM

44 (41)

10 (26)

21 (44)

13 (62)

 

 Other

47 (43)

24 (61)

20 (41)

3 (14)

 

Follow up, n, median months (inerquartile range)

    

NA

 Alive

49

23

20

6

 

39.7 (31.7–52.8)

45.7 (36.5–64.8)

37.1 (26.1–52.3)

33.5 (30.6–42.0)

 

 Dead

59

16

28

15

 

29.0 (19.7–45.3)

37.8 (9.9–64.8)

29.3 (20.0–43.1)

27.4 (19.7–41.7)

 

Total

108

39

48

21

 

36.6 (23.4–48.1)

45.7 (29.9–64.8)

34.6 (21.9–43.8)

30.6 (24.4–41.2)

 
  1. Abbreviations: PLT platelet, HGSC high grade serous carcinoma, Non-HGSC non-high grade serous carcinoma, NA not applicable, PDS primary debulking surgery, NACT neoadjuvant chemotherapy, IDS interval debulking surgery, LNM lymph nodes metastasis beyond abdominopelvic cavity
  2. aTested by one-way ANOVA, Person chi square test or Fisher’s exact test, where applicable