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Table 2 Univariate and multivariate Cox models for OS and PFS

From: Combined score of pretreatment platelet count and CA125 level (PLT-CA125) stratified prognosis in patients with FIGO stage IV epithelial ovarian cancer

Variables OS PFS
Univariate Multivariate Univariate Multivariate
HR 95% CI p HR 95% CI p HR 95% CI p HR 95% CI p
Age (yr)
  < 55 Reference       Reference      
55 1.154 0.686–1.939 0.589     0.933 0.608–1.431 0.751    
Histology, n (%)
 HGSC Reference    Reference    Reference      
 Non-HGSC 1.840 1.053–3.216 0.032 2.121 1.196–3.764 0.010 1.356 0.813–2.264 0.244    
Primary treatment, n (%)
 PDS + chemotherapy Reference       Reference    Reference   
 NACT+IDS/ Chemotherapy alone 1.386 0.819–2.346 0.224     1.659 1.068–2.577 0.024 1.571 1.010–2.444 0.045
Surgery, n (%)
 Optimal surgery Reference    Reference    Reference      
 Suboptimal surgery/no surgery 2.167 1.275–3.681 0.004 2.246 1.314–3.840 0.003 1.763 1.077–2.886 0.024 2.086 1.249–3.486 0.005
Metastatic pattern, n (%)
 Pleural effusion with positive cytology Reference       Reference      
 LNM 0.864 0.421–1.772 0.689     1.291 0.673–2.477 0.443    
 Others 0.527 0.251–1.105 0.090     0.822 0.424–1.597 0.564    
PLT-CA125
 0 Reference    Reference    Reference    Reference   
 1 2.203 1.178–4.119 0.013 2.590 1.356–4.946 0.004 1.553 0949–2.540 0.080 1.751 1.047–2.929 0.033
 2 3.580 1.692–7.576 0.001 4.300 1.976–9.358 < 0.001 2.015 1.108–3.665 0.022 2.131 1.146–3.960 0.017
  1. Abbreviations: OS overall survival, PFS progress-free survival, HR hazard ratio, CI confidence interval, HGSC high grade serous carcinoma, Non-HGSC non-high grade serous carcinoma, PDS primary debulking surgery, NACT neoadjuvant chemotherapy, IDS interval debulking surgery, LNM lymph nodes metastasis.beyond abdominopelvic cavity, PLT platelet