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Table 1 Clinical characteristics of patients

From: Low expression of NCALD is associated with chemotherapy resistance and poor prognosis in epithelial ovarian cancer

 

TCGA(N = 287)

IHC(N = 178)

Clinical characteristics

All (287)

chemoresistant (90)

chemosensitive (197)

P

All (178)

chemoresistant (71)

chemosensitive (107)

P

FIGO stage

 I-II

14 (4.88%)

1 (1.11%)

13 (6.60%)

0.088

38 (22.09%)

8 (11.76%)

30 (28.85%)

0.008*

 III-IV

273 (95.12%)

89 (98.89%)

184 (93.40%)

 

134 (77.91%)

60 (88.24%)

74 (71.15%)

 

 Missing

0

0

0

 

6

3

3

 

Grade

 3

243 (86.48%)

81 (91.01%)

162 (84.38%)

0.130

141 (86.50%)

57 (86.36%)

84 (86.60%)

0.989

 2

38 (13.52%)

8 (8.99%)

30 (15.62%)

 

16 (9.82%)

7 (10.61%)

9 (9.28%)

 

 1

0

0

0

 

6 (3.68%)

2 (3.03%)

4 (4.12%)

 

 Missing

6

1

5

 

15

5

10

 

Histology types

 Serous

287

90 (100.00%)

197 (100.00%)

129 (72.47%)

46 (64.79%)

83 (77.57%)

0.078

 Mucinous

0

0 (00.00%)

0 (00.00%)

 

10 (5.62%)

6 (8.45%)

4 (3.74%)

 

 Others

0

0 (00.00%)

0 (00.00%)

 

39 (21.91%)

19 (26.76%)

20 (18.69%)

 

Surgical debulking

 Optimal

56 (21.54%)

9 (10.59%)

47 (26.86%)

0.003*

71 (64.55%)

28 (53.85%)

43 (74.14%)

0.026*

 Suboptimal

204 (78.46%)

76 (89.41%)

128 (73.14%)

 

39 (35.45%)

24 (46.15%)

15 (25.86%)

 

 Missing

27

5

22

 

68

19

49

 
  1. Note: p value was compared between the chemosensitive patients and the chemoresistant patients, “*” means p < 0.05