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Table 6 Comparison of performance of tests in premenopausal and postmenopausal groups

From: Comparison of the predictive performance of risk of malignancy indexes 1–4, HE4 and risk of malignancy algorithm in the triage of adnexal masses

 

Sensitivity

Specificity

Area Under the Curve (95% confidence interval)

Pre-menopausal

 RMI 1

42.9%

91.5%

0.672 (0.432–0.912)

 RMI 2

42.9%

87.7%

0.653 (0.416–0.890)

 RMI 3

42.9%

87.7%

0.653 (0.416–0.890)

 RMI 4

42.9%

90.6%

0.667 (0.428–0.907)

 HE4

42.9%

98.1%

0.705 (0.459–0.950)

 ROMA

42.9%

91.5%

0.672 (0.432–0.912)

Menopausal

 RMI 1

72.2%

100%

0.861 (0.731–0.992)

 RMI 2

77.8%

91.7%

0.847 (0.715–0.979)

 RMI 3

72.2%

100%

0.861 (0.731–0.992)

 RMI 4

77.8%

95.8%

0.868 (0.742–0.994)

 HE4

77.8%

91.7%

0.653 (0.479–0.827)

 ROMA

77.2%

100%

0.861 (0.731–0.992)

  1. RMI Risk of malignancy index, ROMA Risk Of Malignancy Algorithm, HE4 Human Epididymis Protein 4