Table 4 Univariate and multivariate analyses of prognostic factors for PFS and OS

Age (years)

0.035

0.19

0.014

0.072

  < 50

77

Ref

Ref

Ref

Ref

 ≥ 50

203

1.53 (1.03–2.34)

1.32 (0.87–2.07)

1.80 (1.12–3.03)

1.59 (0.96–2.74)

Platelet counts (×10³/mm³)

<  0.0001

0.0050

<  0.0001

0.022

  < 400

227

Ref

Ref

Ref

Ref

 ≥ 400

53

2.61 (1.76–3.80)

1.89 (1.22–2.87)

2.67 (1.72–4.06)

1.79 (1.09–2.86)

Microcytic hypochromic anemia

0.62

0.30

0.44

0.15

 Present

8

1.17 (0.59–2.07)

1.43 (0.71–2.36)

1.33 (0.62–2.49)

1.75 (0.80–3.42)

 Absent

272

Ref

Ref

Ref

Ref

Histologic subtype

<  0.0001

0.67

<  0.0001

0.21

 Serous

105

Ref

Ref

Ref

Ref

 Non-serous

175

0.36 (0.25–0.51)

0.92 (0.62–1.35)

0.45 (0.30–0.67)

1.33 (0.85–2.05)

FIGO stage

<  0.0001

<  0.0001

<  0.0001

<  0.0001

 I/ II

130

Ref

Ref

Ref

Ref

 III/ IV

150

7.80 (4.94–13.0)

5.47 (3.18–9.69)

7.92 (4.58–14.91)

6.26 (3.30–12.57)

Primary treatment

<  0.0001

0.018

<  0.0001

0.0052

 PDS

207

Ref

Ref

Ref

Ref

 NAC

73

2.99 (2.09–4.26)

1.60 (1.09–2.35)

3.29 (2.18–4.95)

1.90 (1.21–2.98)

Nonmalignant inflammatory condition

0.061

0.55

0.0053

0.24

 Absent

265

Ref

Ref

Ref

Ref

 Present

15

1.97 (0.97–3.57)

0.81 (0.38–1.56)

2.92 (1.42–5.35)

0.64 (0.33–1.37)

Operation achievement

<  0.0001

<  0.0001

<  0.0001

<  0.0001

 Complete, Optimal

262

Ref

Ref

Ref

Ref

 Suboptimal

18

7.31 (4.18–12.0)

4.41 (2.46–7.48)

6.40 (3.46–11.0)

4.60 (2.41–8.24)