Fig. 1

Volcano plot showing differential expression of genes related to the CS group. Data-points (genes) that are located toward the top of the plot and to the right of center are considered to have high statistical significance. Significant immune-related genes related to the CS group, such as IRF1, CXCL9, LTB, CCL5, IL-8, GZMA, PSMB9, CD38, and VCAM1, are identified in the right upper quadrant of the plot, an area that indicates overexpression. (CS: chemosensitive)