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Table 7 Final model for OC recurrence (A) and survival (B) for CA-125 changes 3 months after the treatment

From: Rising serum CA-125 levels within the normal range is strongly associated recurrence risk and survival of ovarian cancer

Variable Recurrence Survival
HR 95%CI P HR 95%CI P
CA-125 change < 0 U/ml 1.00 - - 1.00 - -
CA-125 change 0-5 U/ml 2.78 1.33-5.83 0.0068 2.63 0.82-8.49 0.1048
CA-125 change > 5 U/ml 85.19 17.30–419.59 0.0001 6.56 1.37-31.39 0.0185
Clear cell histology 6.01 1.59–22.66 0.0082 - - -
Endometrioid histology 0.05 0.01–0.42 0.0057 - - -
FIGO stage (I&II vs III&IV) 0.10 0.10 0.0004 - - -
High grade tumor 3.27 3.27 0.0242 3.22 0.98-10.55 0.0541