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Table 7 Final model for OC recurrence (A) and survival (B) for CA-125 changes 3 months after the treatment

From: Rising serum CA-125 levels within the normal range is strongly associated recurrence risk and survival of ovarian cancer

Variable

Recurrence

Survival

HR

95%CI

P

HR

95%CI

P

CA-125 change < 0 U/ml

1.00

-

-

1.00

-

-

CA-125 change 0-5 U/ml

2.78

1.33-5.83

0.0068

2.63

0.82-8.49

0.1048

CA-125 change > 5 U/ml

85.19

17.30–419.59

0.0001

6.56

1.37-31.39

0.0185

Clear cell histology

6.01

1.59–22.66

0.0082

-

-

-

Endometrioid histology

0.05

0.01–0.42

0.0057

-

-

-

FIGO stage (I&II vs III&IV)

0.10

0.10

0.0004

-

-

-

High grade tumor

3.27

3.27

0.0242

3.22

0.98-10.55

0.0541