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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: circRNA-UBAP2 promotes the proliferation and inhibits apoptosis of ovarian cancer though miR-382-5p/PRPF8 axis

Fig. 5

miR-382-5p targeted PRPF8. a, The binding site of miR-382-5p and PRPF8 was predicted by starBase. b, The interaction of PRPF8 and miR-382-5p was determined by dual-luciferase reporter gene system. *P < 0.05 vs NC group. c, Overexpression of miR-382-5p decreased the expression of PRPF8 in SKOV3and A2780 cells measured by western blotting. *P < 0.05 vs NC group. d, Expression of PRPF8 in ovarian cancer tissues and adjacent tissues were measured by RT-qPCR assay. **P < 0.01 vs adjacent tissues. e, There was a negative correlation existed between expression level of PRPF8 and miR-382-5p in ovarian cancer tissues measured by RT-qPCR assay. P < 0.0001

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