|
Category
|
MOSI score
|
All data (n = 337)
|
Only normo-responders (n = 255)
|
|---|
|
Prevalence
|
Test accuracy
|
PPV
|
NPV
|
Prevalence
|
Test accuracy
|
PPV
|
NPV
|
|---|
|
High-quality Embryo on Day 2 (≥6)
|
2.1
|
27.3%
|
33.2%
|
28.6%
|
88.5%
|
27.1%
|
27.1%
|
27.1%
|
N/A
|
|
2.6
| |
43.4%
|
32.0%
|
93.5%
| |
35.7%
|
29.4%
|
95.8%
|
|
3.1
| |
54.3%
|
36.0%
|
89.6%
| |
50.2%
|
33.7%
|
88.3%
|
|
3.6
| |
68.5%
|
45.2%
|
86.4%
| |
69.0%
|
45.1%
|
85.0%
|
|
4.1
| |
71.8%
|
47.1%
|
76.2%
| |
73.3%
|
57.1%
|
73.8%
|
|
4.6
| |
71.5%
|
16.7%
|
72.5%
| |
72.9%
|
N/A
|
72.9%
|
|
Blastocysts (≥6)
|
2.0
|
35.9%
|
39.5%
|
36.9%
|
80.0%
|
35.7%
|
35.7%
|
35.7%
|
N/A
|
|
2.5
| |
44.8%
|
39.1%
|
89.5%
| |
35.7%
|
35.7%
|
N/A
|
|
3.0
| |
54.9%
|
43.4%
|
81.4%
| |
49.0%
|
39.8%
|
76.6%
|
|
3.5
| |
68.0%
|
54.0%
|
80.7%
| |
66.3%
|
52.1%
|
78.3%
|
|
4.0
| |
69.4%
|
64.1%
|
70.7%
| |
68.2%
|
75.0%
|
67.7%
|
|
4.5
| |
65.3
|
70.0%
|
65.1%
| |
64.3%
|
N/A
|
64.3%
|
|
Rate of blastocyst/ova captured (≥35%)
|
2.0
|
18.1%
|
22.8%
|
18.6%
|
90.0%
|
18.0%
|
18.0%
|
18.0%
|
N/A
|
|
2.5
| |
28.2%
|
19.7%
|
94.7%
| |
18.0%
|
18.0%
|
N/A
|
|
3.0
| |
43.0%
|
22.1%
|
91.2%
| |
37.6%
|
20.4%
|
89.1%
|
|
3.5
| |
61.4%
|
28.6%
|
91.5%
| |
62.0%
|
28.2%
|
90.6%
|
|
4.0
| |
74.8%
|
31.3%
|
85.0%
| |
79.6%
|
35.0%
|
83.4%
|
|
4.5
| |
80.7%
|
30.0%
|
82.3%
| |
82.0%
|
N/A
|
82.0%
|
|
4.8
| |
81.3%
|
0%
|
81.8%
| |
82.0%
|
N/A
|
82.0%
|
- Abbreviations: MOSI modified ovarian sensitivity index, NPV negative predictive value, and PPV Positive predictive value
- Bold values are the results based on the cutoff using the highest Youden index based on the Receiver-operating characteristic curve
