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Table 1 The Characteristics and Newcastle–Ottawa scale score of studies included in the meta-analysis

From: Can polymorphisms of AMH/AMHR2 affect ovarian stimulation outcomes? A systematic review and meta-analysis

Study Country/Ethnicity SNPs evaluated No. of patients Mean age ± SD Protocol Study design Genotyping HWE Outcomes* NOS scores
Lledó, 2019 [18] Spain/Caucasian AMH/ AMHR2 124 23.9 ± 3.5 GnRH-A prospective PCR Yes 1.2.3 6
Wu, 2019 [21] China/Asian AMH/AMHR2 635 NA GnRHa prospective PCR Yes 1.2.3.4.7 6
Lazaros, 2016 [17] Greece/Caucasian AMHR2 300 28–38 GnRHa prospective PCR Yes 3. 4. 7
Cerra, 2016 [15] UK/multiple AMH/AMHR2 603 NA GnRHa/GnRH-A prospective TaqMan No metion 2. 3. 5. 8 6
Peluso, 2015 [19] Brazil AMH/AMHR2 186 32.5 ± 3.5 GnRH-A prospective TaqMan Yes 3. 6. 7. 8. 6
Wang, 2015 [20] China/Asian AMH 122 NA GnRHa retrospective PCR Yes 3 7
Karagiorga, 2015 [16] Greece AMH/AMHR2 151 36 ± 5 GnRHa/GnRH-A prospective PCR Yes 1. 2. 3. 4. 7
  1. *Outcomes: 1. stimulation duration; 2. Gn dosage; 3. No. of oocytes retrieved; 4. clinical pregnancy rate; 5. live birth; 6. AMH level; 7. No. of MII oocytes; 8. No. of embryo. HWE Hardy-Weinberg equilibrium