Telomere length in granulosa cells and leukocytes: a potential marker of female fertility? A systematic review of the literature

Table 5 Summary table of the different studies

Authors	Samples	Subjects	Setting	Method	Results
Butts et al. 2009 [38]	Granulosa cells	12 POF 42 controls	TL	qPCR	Shorter telomere in POF
Butts et al. 2009 [38]	Granulosa cells	12 POF 42 controls	TA	PCR TRAPeze Telomerase Detection Kit	Absence of TA more frequent in POF
Hanna et al. 2009 [39]	Leukocytes	34 POF 108 controls	TL	qPCR	Longer telomere in POF
Xu et al. 2017 [42]	Granulosa cells	120 POF 90 controls	TL	qPCR	Shorter telomere in POF
	Leukocytes	120 POF 279 controls	TL	qPCR	Shorter telomere in POF
	Granulosa cells	31 POF 38 controls	TA	PCR Q-TRAP	TA level lower in POF
Miranda-Furtado et al. 2018 [40]	Leukocytes	46 POF 75 controls	TL	qPCR	Shorter telomere in POF
Sayban et al. 2018 [41]	Leukocytes	40 POF 40 controls	TL	qPCR	Longer telomere in POF

ISSN: 1757-2215