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Table 5 Summary table of the different studies

From: Telomere length in granulosa cells and leukocytes: a potential marker of female fertility? A systematic review of the literature

Authors Samples Subjects Setting Method Results
Butts et al. 2009 [38] Granulosa cells 12 POF
42 controls
TL qPCR Shorter telomere in POF
Granulosa cells 12 POF
42 controls
TA PCR TRAPeze Telomerase Detection Kit Absence of TA more frequent in POF
Hanna et al. 2009 [39] Leukocytes 34 POF
108 controls
TL qPCR Longer telomere in POF
Xu et al. 2017 [42] Granulosa cells 120 POF
90 controls
TL qPCR Shorter telomere in POF
Leukocytes 120 POF
279 controls
TL qPCR Shorter telomere in POF
Granulosa cells 31 POF
38 controls
TA PCR Q-TRAP TA level lower in POF
Miranda-Furtado et al. 2018 [40] Leukocytes 46 POF
75 controls
TL qPCR Shorter telomere in POF
Sayban et al. 2018 [41] Leukocytes 40 POF
40 controls
TL qPCR Longer telomere in POF
  1. TL Telomere length
  2. TA Telomerase activity