Table 3 The results of WB, IF, Transwell and Would healing assay (\( \overline{\mathrm{x}} \) ± SD)

WB (relative gray value)

Bax

0.03 ± 0.00

0.15 ± 0.01**

0.14 ± 0.01**

0.14 ± 0.01**

0.10 ± 0.02**

0.09 ± 0.00**

bcl-2

0.24 ± 0.01

0.06 ± 0.01**

0.06 ± 0.01**

0.06 ± 0.01**

0.18 ± 0.01**

0.19 ± 0.02**

p-VEGFR-2

0.14 ± 0.01

0.03 ± 0.00**

0.04 ± 0.00**

0.04 ± 0.00**

0.13 ± 0.01

0.09 ± 0.00**

MMP-2

0.16 ± 0.01

0.03 ± 0.00**

0.04 ± 0.00**

0.04 ± 0.00**

0.09 ± 0.01**

0.09 ± 0.00**

IF (positive rate%)

Bax

2.7% ± 0.29

23.07% ± 1.13**

21.57% ± 0.67**

21.8% ± 1.8**

12.4% ± 1.07**

10.57% ± 0.68**

bcl-2

25.7% ± 0.65

7.57% ± 1.11**

7.4% ± 1.1**

8.2% ± 1.2**

13.33% ± 1.96**

13.73% ± 0.71**

p-VEGFR-2

27.8% ± 0.86

6.8% ± 1.51**

7.5% ± 0.94**

8.4% ± 0.88**

24.47% ± 2.27

17.7% ± 0.52**

MMP-2

27.1% ± 1.7

7.97% ± 1.2**

9.83% ± 1.01**

11.13% ± 0.4**

21.07% ± 1.14**

22.27% ± 0.97**

391 ± 21.7

6 ± 1.3**

12 ± 2.6**

14 ± 1.9**

197 ± 29.9**

216 ± 26.1**

Wound healing (Area recovery%)

12 h

63.54 ± 4.48

−6.56 ± 0.39**

−5.28 ± 0.53**

−4.5 ± 0.39**

1.03 ± 0.05**

−2.46 ± 0.27**

24 h

84.88 ± 2.15

−14.8 ± 0.7**

−14.37 ± 0.73**

−14.15 ± 0.61**

1.51 ± 0.07**

−2.51 ± 1.18**