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Fig. 6 | Journal of Ovarian Research

Fig. 6

From: Long non-coding RNA PTPRG-AS1 promotes cell tumorigenicity in epithelial ovarian cancer by decoying microRNA-545-3p and consequently enhancing HDAC4 expression

Fig. 6

HDAC4 reintroduction abolishes the inhibitory actions of PTPRG-AS1 knockdown on EOC cells. a The overexpression efficiency of pc-HDAC4 in OVCAR3 and CAOV-3 cells was determined by RT-qPCR. b-e si-PTPRG-AS1 in parallel with pc-HDAC4 or pcDNA3.1 was introduced into OVCAR3 and CAOV-3 cells. Proliferation, apoptosis, migration, and invasion were determined by CCK-8 assay, flow cytometry analysis, Transwell cell migration assay, and Transwell cell invasion assay, respectively. *P < 0.05 and **P < 0.01

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