Fig. 5
From: STAT4 targets KISS1 to promote the apoptosis of ovarian granulosa cells
STAT4 inhibits the synthesis of E2 in porcine GCs. Effects of pcDNA3.1-STAT4 (a) and STAT4-siRNA (b) on the relative mRNA levels of Star, CYP17, 3B-HSD, 17B-HSD, and CYP19A; c Concentrations of E2 was depressed by pcDNA3.1-STAT4; d Concentrations of E2 was stimulated by STAT4-siRNA; e Effects of pcDNA3.1-STAT4 on the relative mRNA levels of ESR1 and ESR2; f Effects of STAT4-siRNA on the relative mRNA levels of ESR1 and ESR2. ** indicates P < 0.01; * indicates P < 0.05. Data were represented as means ± SD