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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Dysregulation of lnc-SNHG1 and miR-216b-5p correlate with chemoresistance and indicate poor prognosis of serous epithelial ovarian cancer

Fig. 4

Knockdown of lnc-SNHG1 and overexpression of miR-216b-5p stimulated paclitaxel sensitivity in A2780/Taxol cells through inhibiting cell growth and migration and promoting apoptosis. a qRT-PCR analysis of lnc-SNHG1 and miR-216b-5p expression in A2780/Taxol cell lines after transfecion. b and c Proliferation capacity was determined after the downregulation of SNHG1 and the overexpression of miR-216b-5p in A2780/Taxol cells using CCK-8 assay and colony formation assay. d Migration ability was determined using the wound healing assay after transfection. e Flow cytometry analysis of apoptosis was performed. GAPDH was used as the control. ***P < 0.001

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Journal of Ovarian Research

ISSN: 1757-2215

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